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Clotrimazole cream for thrush on nipples, vulva) at 6:00 PM. The other side was given two 4mg tablets of ceftriaxone at bedtime and 10:00 PM. All patients received a 2nd round of the antibiotic treatment at 8:00 PM the next day on a 0.5% parenteral antibiotic such as ceftriaxone with and without doxycycline. The main outcome measures included presence or absence of a bacterial meningitis, symptoms, and hospital admissions. RESULTS: We found no difference in the overall prevalence of meningitis between the two groups, with a mean difference of 2.8% (95% CI 0.8-5.5). A total of 26 patients in the group who received ceftriaxone and 6 of 27 patients in the placebo group were admitted for meningitis. The meningitis rate in group who had received ceftriaxone was not significantly different from the rate in group who had received placebo (3.6/100 vs. 3.3/100, p = 0.7, χ2 analysis) or the rates in patients who had not received antibiotic treatment (3/100 vs. 0/100, p = 0.1, χ2 analysis). The meningitis rate in clotrimazol globulki otc ceftriaxone group had a greater influence on clinical and laboratory parameters than did those in the placebo group (p < 0.001). No significant differences had been noted between the two groups regarding antibiotic administration (p = 0.9, Wilcoxon drugstore free international shipping rank sum test). CONCLUSION: Overall, both the groups had similar prevalence of meningitis but the rate clinical and laboratory changes in the ceftriaxone group was higher than in the placebo group which is likely to be a contributing factor the increased hospitalisations.
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